Geek Science

BREAKTHROUGH: Scientists See Gene Activation In Human Brain For The First Time

BREAKTHROUGH: Scientists See Gene Activation In Human Brain For The First Time
Written by Agboola Sodiq
The imaging method tracks molecules active in several neurological diseases.

When it comes to neurological disorders like Alzheimer’s and schizophrenia, along with addiction and depression, a certain enzyme has gotten a lot of attention as a major actor in each: histone deacetylases (HDACs). Scientists recently developed a new imaging technique to see them in action, witnessing changes in gene activity in the brain for the first time.

Dysfunction in epigenetics, or alterations in gene expression that affect organism function, is responsible for many neurological disorders, including those above.

Scientists know HDACs are involved in changing those expressions, but lack specific information.. To study the difference in the molecules’ activity in healthy brains versus the afflicted, researchers spent seven years creating a compound, [11C]Martinostat, that would help examine them at work in the brain.

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Agboola Sodiq

To the outside world, I'm just an ordinary geek. But in secret, I work to make my world information-safe. In order to succeed, I must become someone else... I must become something else.